Talk by Prof. Argyris Politis: ‘Probing the conformational dynamics of membrane proteins by HDX-MS’

Talk by Prof. Argyris Politis: ‘Probing the conformational dynamics of membrane proteins by HDX-MS’

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On October 13th, Prof. Argyris Politis delivered an engaging talk at the University of Patras, Medical School, Department of Biomedical Sciences focusing on the role of Mass Spectrometry (MS) in advancing structural biology.

The talk highlighted the importance of exploring structural dynamics in physiological environments, emphasizing how lipid-modulated conformational changes in membrane proteins can be probed through Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS).

This lecture offered valuable insights into how next-generation MS-based approaches are reshaping our understanding of biomolecular mechanisms, bridging the gap between static structures and dynamic biological function.

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