On 27 February 2026, the MASSTRUCT Project hosted an Open Lab Day at the Politis Lab (Room 306/307) at Biomedical Sciences Research Center Alexander Fleming.

The event introduced participants to Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS), a powerful analytical technique used to study protein structure, dynamics, and interactions. A total of 15 participants attended the event and had the opportunity to observe how HDX-MS experiments are performed and learn about its applications in structural biology research.

Highlights of the event

• Introduction to the principles of HDX-MS
• Demonstration of real-time data acquisition
• Overview of HDX-MS data analysis workflows
• Discussion of research applications in biomolecular and structural studies

The Open Lab Day provided a valuable opportunity for participants to engage with researchers, explore advanced analytical technologies, and gain insight into how HDX-MS contributes to the understanding of protein structure and function.